• Most common form of hereditary stroke disorder
  • Full form: Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
  • Pathogenesis: Mutation in NOTCH3 gene
  • Remember: CADASIL: NOTCH3
  • Age: Young and middle age
  • C/F:
    1. Recurrent lacunar and subcortical white matter ischemic strokes
    2. Vascular dementia
  • MRI finding: Widespread confluent white matter hyperintensities
  • Location: Anterior temporal lobe and external capsule.

How useful was this post?

Click on a star to rate it!

Average rating 4.8 / 5. Vote count: 6

No votes so far! Be the first to rate this post.

1 thought on “CADASIL”

Leave a Reply

Your email address will not be published.