Energectics of β-oxidation of fat

4.8
(4)

Site: Mitochondrial matrix

Rate limiting enzyme: Carnitine acyl transferase 1 (CAT-1)

Steps:

Analysis:

  • For any fatty acid, activation requires 2 ATP
  • For every cycle of β-oxidation (1.5 +2.5 +10) = 14 ATP generated.

MCQ 1

How many ATP is generated in complete β-oxidation of Palmitic acid (16C)?

  • For activation, 2 ATP is required
  • 16C compound requires (16/2)-1 = 7 cycles of β-oxidation
  • ATP generated in 7 cycles of β-oxidation= (14X7)= 98 ATP
  • 1 additional Acetyl-CoA is produced at the last step
  • At the last step, an additional 10 ATP generated
  • So, neat ATP generation = (98+10-2) = 106 ATP.

 

MCQ 2

How many ATP is generated in complete β-oxidation of Stearic acid (18C)?

  • For activation, 2 ATP is required
  • 18C compound requires (18/2)-1 = 8 cycles of β-oxidation
  • ATP generated in 8 cycles of β-oxidation= (14X8)= 112 ATP
  • 1 additional Acetyl-CoA is produced at the last step
  • At the last step, an additional 10 ATP generated
  • So, neat ATP generation = (112+10-2) = 120 ATP.

Disclaimer:

Images used in this webpage to describe the topic(s) properly to the audience might be copyrighted under other person(s) or publishing house(s) or respective company. We have solely used them for non-commercial educational purpose only; not intended to any unfair means or copyright violation. Still if you want any image(s) to be removed from this webpage, please leave a message to admin@mdmspgprep.com with proper evidence of authorization (link to original work and allegedly infringing url) and we will not hesitate to process your request as early as possible and delete the respective image(s). Thank you for cooperating with us.

How useful was this post?

Click on a star to rate it!

Average rating 4.8 / 5. Vote count: 4

No votes so far! Be the first to rate this post.

Leave a Reply

Your email address will not be published.