Muscle contraction

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Events:

Pathology:

Differences:

Isometric vs. Isotonic contraction:

Concept of optimum length:

  • Frank-Starling law: During an isometric muscle contraction, more the initial length of the muscle, more the total & active tension generated BUT upto a physiological limit, beyond which a further increase in initial length will decrease the total & active tension generated
  • Optimum length refers to that initial length at which, if a muscle contracts isometrically- the total and active tension generated is maximum, i.e. maximum no. of actin & myosin cross bridge formation & maximum overlap takes place.

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